Dr. Abud Bakri, MD: Thymus Health, Circadian Biology, and the Truth About Peptides

Show notes

Most longevity conversations focus on the brain, heart, muscle, and metabolism. Far less attention goes to the thymus, an immune organ that starts shrinking almost as soon as puberty ends, and new research suggests it may be quietly linked to fertility, hormones, and even how millions of women taking birth control are aging on the inside.

I sit down with Dr. Abud Bakri, a board-certified internal medicine physician and hospitalist who founded Systems, a performance and longevity practice built around treating the body system by system rather than symptom by symptom.

We start with the foundations that determine whether any advanced intervention can actually work: light exposure, circadian timing, mitochondrial health, metabolic function, and the parts of modern life working against all of it.

Then we get into the thymus itself: why it shrinks after puberty, what that has to do with an unexpected finding in ovarian development, and a harder question Dr. Bakri raises about whether birth control may be accelerating that shrinkage in ways no one is currently studying.

We close on peptides: why Dr. Bakri treats them like drugs rather than supplements, what separates receptor-based peptides from the ones we understand far less, what we actually know about BPC-157, thymosin alpha-1, SS-31, and GHK-Cu, and how a peptide protocol could eventually be timed to a woman's cycle instead of applied the same way to everyone.

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