Carolina Reis Oliveira, PhD: Senescent Cells, Retinol Myths, and the Skin Barrier Body Connection

Show notes

Most skincare is designed to improve how aging looks. But can it change what is happening inside the skin itself?

In this conversation, I sit down with Carolina Reis Oliveira, PhD, co-founder and CEO of OneSkin, to explore what actually drives skin aging at the cellular level. Carolina explains how senescent “zombie” cells, UV exposure, inflammation, hormonal changes and a weakened skin barrier affect how skin functions, not just how it looks.

Get OneSkin's new Rich Cream and the rest of the OS-01 line at:

oneskin.co/KAYLA with code KAYLA.

We break down the benefits and limitations of retinol, why chronic redness and flaking are not signs that a product is working better, and whether popular ingredients such as NAD+ precursors, methylene blue and GHK-Cu can penetrate the skin and remain stable. We also discuss collagen supplementation, red light therapy, hyperbaric oxygen, sauna, exercise, sun exposure and the relationship between skin-barrier health and systemic inflammation.

Carolina also shares the science behind OneSkin's OS-01 peptide and its new Face Rich Cream, including findings related to collagen, hyaluronic acid, elastin, filaggrin, hydration, firmness and fine lines.

In this conversation:

-Why many anti-aging products target visible symptoms rather than the biology of skin aging

-How senescent “zombie” cells contribute to inflammation and tissue decline

-How to use retinol without chronically damaging the skin barrier

-Why ingredient penetration, stability and formulation matter

-How skin-barrier dysfunction may affect inflammation throughout the body

-What collagen, red light, hyperbaric oxygen, sauna and exercise can do for the ski

- What OneSkin found when testing GHK-Cu copper peptides

-Why moisturizer alone may not solve age-related dryness

-How OS-01 is designed to target the underlying biology of skin aging

Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.

https://kayla-barnes-lentz.circle.so/female-longevity-community

Optimize your sleep with the Eight Sleep Pod.

Get up to $350 off at https://www.eightsleep.com/Kayla with code “KAYLA”

Support lean muscle and recovery with PerfectAmino essential amino acids: https://bodyhealth.com/products/perfectamino“Kayla20”

Connect with Kayla:

Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter:https://x.com/femalelongevity

Website:https://www.kaylabarnes.com/

Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054

Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com