
The Human Upgrade: Biohacking for Longevity & Performance
Jonny Miller on Nervous System Mastery, Grief, and Why High Performers Can't Afford to Stay Stuck in Their Heads
Your nervous system is running every decision, relationship, and reaction in your life, and you won't notice how much it's costing you until something breaks. This episode gives you the exact framework for building real nervous system mastery instead of running on autopilot until it fails.
Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR
Host Dave Asprey sits down with Jonny Miller, host of the Inner Frontier Podcast and founder of Nervous System Mastery, who has taught more than 1,000 people how to build the skills of interoception, self-regulation, and emotional fluidity. A former Silicon Valley founder turned nervous system expert, Jonny brings a rare mix of rational, data-driven thinking and deep somatic work to a field most high performers avoid entirely.
They break down why interoception, self-regulation, and emotional fluidity are the three learnable skills behind every major shift in performance, relationships, and decision-making, and why most high achievers have spent their whole lives disconnected from what's happening below the neck. Jonny introduces the half-life of reactivity, his framework for measuring how quickly someone can move from triggered back to calm, and explains how free diving became his gateway into surrender, breath work, and pressure equalization as a form of high-stakes meditation. Dave shares his own parallel journey through nervous system work, including lessons from running 40 Years of Zen and a costly business betrayal that reshaped how he reads people. Dave and Jonny also open up about grief, including Jonny's experience losing his fiancée and later his mother, and how community and co-regulation shape how fast someone actually heals.
You'll Learn:
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Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: Jonny Miller, Inner Frontier Podcast, Nervous System Mastery, interoception, self-regulation, emotional fluidity, half-life of reactivity, free diving, breathwork, nervous system regulation, somatic healing, grief processing, co-regulation, congruence, trauma response, boundary setting, narcissism, hiring intuition, cold plunge, surrender, NSDR, yoga nidra, Breath Buddy, biohacking, high performance, 40 Years of Zen, psychedelic integration, Silicon Valley founder, emotional resilience
Resources:
• Nervous System Mastery Course: https://www.nsmastery.com/
• Listen To Jonny’s Podcast ‘The Inner Frontier’ at: https://open.spotify.com/show/1lGD5wIfhnE4bepja42C9S
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Timestamps:
00:00 – Trailer
01:10 – Losing His Fiancée
04:28 – Nervous System Mastery
11:52 – Community & Co-Regulation
17:37 – From Head to Body
22:52 – Surrender & Free Diving
28:54 – Half-Life of Reactivity
35:33 – Congruence & the $100M Lesson
38:58 – Stupidity, Narcissism & Intuition
50:22 – Biohacking Trojan Horses
59:11 – Breath Buddy & Outro
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